Vitamin D Supreme

High-Dose Vitamin D3 (5,000 IU / 125 mcg as Cholecalciferol) with Vitamin K1 (1,000 mcg as Phytonadione), Vitamin K2 (1,000 mcg as MK-4), and GG-Gold® Geranylgeraniol (5 mg) for Nutrient Repletion, Optimal Bone Health, Cardiovascular Health, Arterial Strength and Elasticity, Immune System Balance, and Calcium Absorption and Utilization*

Key Performance Benefits

• Supports optimal bone health with higher-dose vitamin D3*

• Supports cardiovascular health*

• Promotes arterial strength and elasticity*

• Helps maintain healthy immune system balance*

• Optimizes calcium absorption and utilization*

• Provides repletion-level vitamin D for those with inadequate sun or dietary intake*

What This Product Is

Vitamin D Supreme provides targeted quantities of vitamin D3 and vitamin K as both vitamins K1 and K2 (as MK-4), along with geranylgeraniol (GG), a compound produced naturally in the body, to help promote optimal bone and heart health and maintain proper immune system balance.* Vitamin D Supreme contains 5,000 IU (125 mcg) of vitamin D3 (cholecalciferol) per serving, making it ideal when nutrient repletion is required for individuals who do not get adequate sunlight exposure or dietary sources of vitamins D and K.

Vitamins D and K are fat-soluble vitamins with broad influences on human physiology. Vitamin D is a key player in supporting bone health and calcium regulation in the body, and it is also essential for proper immune function. Vitamin K supports bone and heart health and is critical for directing the transport of dietary calcium into the bones and teeth and away from the arteries. This division of labor is why the two vitamins are paired: vitamin D increases the amount of calcium the body absorbs, while vitamin K helps direct that calcium to where it belongs.*

Supplementing vitamin D without adequate vitamin K may increase the chances of calcium being deposited in the arteries and other soft tissues, which may have a negative impact on arterial health.* Current research suggests that the combined supplementation of both vitamins D and K can be more effective than either vitamin alone for both bone and cardiovascular health.* By delivering a higher, repletion-level dose of vitamin D alongside a complete vitamin K complex and geranylgeraniol, Vitamin D Supreme is designed to raise vitamin D status while supporting proper calcium utilization.*

Mechanism of Action

High-Dose Vitamin D3 for Repletion*

Vitamin D3 (5,000 IU / 125 mcg as cholecalciferol) provides a higher dose appropriate when nutrient repletion is required for individuals with vitamin D deficiency or insufficiency. Vitamin D supports bone health through enhanced calcium absorption and regulation, supports immune system balance, and contributes to overall skeletal integrity.*

Vitamins K1, K2, and Geranylgeraniol for Calcium Direction*

Vitamin K1 (1,000 mcg as phytonadione) and vitamin K2 (1,000 mcg as MK-4) activate the vitamin K–dependent proteins that direct dietary calcium into bones and teeth while helping discourage calcium deposition in the arteries.* GG-Gold® (5 mg) geranylgeraniol is a precursor the body uses in the production of MK-4, supporting the body’s own vitamin K2 status alongside the supplemented forms.*

Synergistic Bone and Cardiovascular Support*

Because the higher vitamin D dose increases calcium absorption, the accompanying vitamin K complex becomes especially important for ensuring that calcium is directed toward the skeleton rather than soft tissue. Together, the repletion-level vitamin D and complete vitamin K complex support optimal bone health, arterial strength and elasticity, and cardiovascular health, while helping maintain healthy immune system balance.*

Applications

• Individuals requiring vitamin D repletion due to deficiency or insufficiency*

• Those not getting adequate sunlight exposure or dietary vitamin D sources*

• Individuals needing higher-dose vitamin D with protective vitamin K support*

• Those seeking bone health, cardiovascular, and immune system support*

• Individuals wanting proper calcium direction with high-dose vitamin D supplementation*

Key Ingredients / Formula Highlights

High-Dose Synergistic D and K Formula

Vitamin D3 (5,000 IU / 125 mcg cholecalciferol), vitamin K1 (1,000 mcg phytonadione), vitamin K2 (1,000 mcg MK-4), and GG-Gold® geranylgeraniol (5 mg) combined in a single daily capsule.

GG-Gold® Geranylgeraniol (5 mg)

A naturally occurring compound and precursor in the body’s production of MK-4, included to support endogenous vitamin K2 status alongside the supplemented vitamin K forms.

Repletion-Level Clean Formula

Available as VDS030 (30 capsules), VDS060 (60 capsules), and VDS180 (180 capsules). Gluten-free, dairy-free, soy-free, and non-GMO. Caution with Coumadin, warfarin, or anticoagulant medications.

Suggested Use

Take 1 capsule per day with a meal or as directed by your health-care practitioner. Consult your health-care practitioner before using this product if you are taking Coumadin, warfarin, or other anticoagulant medications.

Product Questions

How does Vitamin D Supreme compare to Vitamin D Synergy?

Both formulas contain the same vitamin K blend (K1 1,000 mcg, K2 1,000 mcg as MK-4, and GG-Gold® 5 mg). Vitamin D Supreme provides 5,000 IU (125 mcg) of vitamin D3 for nutrient repletion when deficiency or insufficiency is present. Vitamin D Synergy provides 2,000 IU (50 mcg) of vitamin D3 for daily maintenance of optimal vitamin D status. Choose Vitamin D Supreme when higher doses are needed, or Vitamin D Synergy for ongoing daily maintenance.*

Why are vitamins D and K combined in one formula?

The two vitamins work together: vitamin D increases the amount of calcium the body absorbs, while vitamin K activates the proteins that direct that calcium into bones and teeth and away from the arteries. Supplementing vitamin D without adequate vitamin K may increase the chances of calcium being deposited in arteries and soft tissues. Pairing a repletion-level vitamin D dose with a complete vitamin K complex supports proper calcium utilization for both bone and cardiovascular health.*

When is the higher dose of vitamin D3 appropriate?

Vitamin D Supreme with 5,000 IU may be ideal when nutrient repletion is required for individuals who do not get adequate sunlight exposure or dietary sources of vitamins D and K, or for those with documented vitamin D deficiency or insufficiency. Your health-care practitioner can help determine the appropriate dose based on blood levels and individual needs.*

Who may benefit most from Vitamin D Supreme?

Individuals with vitamin D deficiency or insufficiency requiring nutrient repletion, those with limited sunlight exposure or dietary vitamin D intake, people needing higher-dose vitamin D with protective vitamin K support for proper calcium direction, and anyone seeking comprehensive bone, cardiovascular, and immune system support with a higher vitamin D dose.*

Practitioner Reference

Vitamin D Supreme is positioned within the Designs for Health Foundational Health category. Available as VDS030 (30 capsules), VDS060 (60 capsules), and VDS180 (180 capsules). GG-Gold® is a registered trademark of American River Nutrition, LLC. Caution advised for individuals taking Coumadin, warfarin, or other anticoagulant medications. This product is intended for use under the guidance of a licensed health-care practitioner.